Open Mind, bred by Due Process Stables in 1986, was sired by Deputy Minister-Stage Luck, by Stage Door Johnny. Open Mind debuted on August 15, 1988 in a New Jersey-bred maiden race at Monmouth Park open to males and won easily. She returned 15 days later to win the New Jersey Breeders' Stakes at Monmouth. Open Mind would win the 1988 Breeder' Cup Juvenile Fillies by 1 ¾ lengths en route to earning the Eclipse Award as Champion two-year-old filly
The D. Wayne Lukas trainee followed up her championship campaign by having more success as a three-year-old when she won her first eight races including the Kentucky Oaks, Acorn, Mother Goose, Coaching Club American Oaks and the Alabama. Her win in the Coaching Club American Oaks completed her sweep of the New York Filly Triple Crown series and she received the Eclipse Award as Champion three-year-old filly.
Open Mind was owned by Eugene Klein, who also owned the National Football League's San Diego Chargers, who was no stranger to successful horses as he owned such notables as Tank's Prospect, Lady's Secret, Winning Colors, Capote, Life's Magic, Is it True, Success Express, and Twilight Ridge.
Open Mind was inducted in the National Museum of Racing and Hall of Fame in 2011 and the New Jersey-bred Hall of Fame in 2012.